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S153. IMPAIRED THETA PHASE-COUPLING BETWEEN HIPPOCAMPUS AND MEDIAL PREFRONTAL CORTEX IN SCHIZOPHRENIA

BACKGROUND: A genetic schizophrenia (Scz) mouse model has impaired hippocampal-prefrontal synchrony during spatial working memory (Sigurdsson et al., 2000, Nature). These Df(16)A(+/-) mice (models of the human 22q11.2 microdeletion) have impaired mPFC phase coupling to hippocampal theta (1–8 Hz) osc...

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Detalles Bibliográficos
Autores principales: Adams, Rick, Bush, Daniel, Zheng, Fanfan, Meyer, Sofie, Kaplan, Raphael, Orfanos, Stelios, Reis Marques, Tiago, Howes, Oliver, Burgess, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7234681/
http://dx.doi.org/10.1093/schbul/sbaa031.219