Cryo-EM structure in situ reveals a molecular switch that safeguards virus against genome loss

The portal protein is a key component of many double-stranded DNA viruses, governing capsid assembly and genome packaging. Twelve subunits of the portal protein define a tunnel, through which DNA is translocated into the capsid. It is unknown how the portal protein functions as a gatekeeper, prevent...

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Detalles Bibliográficos
Autores principales: Bayfield, Oliver W, Steven, Alasdair C, Antson, Alfred A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Structural Biology and Molecular Biophysics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7234808/
https://www.ncbi.nlm.nih.gov/pubmed/32286226
http://dx.doi.org/10.7554/eLife.55517

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7234808/
https://www.ncbi.nlm.nih.gov/pubmed/32286226
http://dx.doi.org/10.7554/eLife.55517

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