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Cryo-EM structure in situ reveals a molecular switch that safeguards virus against genome loss
The portal protein is a key component of many double-stranded DNA viruses, governing capsid assembly and genome packaging. Twelve subunits of the portal protein define a tunnel, through which DNA is translocated into the capsid. It is unknown how the portal protein functions as a gatekeeper, prevent...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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eLife Sciences Publications, Ltd
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7234808/ https://www.ncbi.nlm.nih.gov/pubmed/32286226 http://dx.doi.org/10.7554/eLife.55517 |