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A helminth-derived suppressor of ST2 blocks allergic responses

The IL-33-ST2 pathway is an important initiator of type 2 immune responses. We previously characterised the HpARI protein secreted by the model intestinal nematode Heligmosomoides polygyrus, which binds and blocks IL-33. Here, we identify H. polygyrus Binds Alarmin Receptor and Inhibits (HpBARI) and...

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Detalles Bibliográficos
Autores principales:	Vacca, Francesco, Chauché, Caroline, Jamwal, Abhishek, Hinchy, Elizabeth C, Heieis, Graham, Webster, Holly, Ogunkanbi, Adefunke, Sekne, Zala, Gregory, William F, Wear, Martin, Perona-Wright, Georgia, Higgins, Matthew K, Nys, Josquin A, Cohen, E Suzanne, McSorley, Henry J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2020
Materias:	Immunology and Inflammation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7234810/ https://www.ncbi.nlm.nih.gov/pubmed/32420871 http://dx.doi.org/10.7554/eLife.54017

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