UGCG overexpression leads to increased glycolysis and increased oxidative phosphorylation of breast cancer cells

The only enzyme in the glycosphingolipid (GSL) metabolic pathway, which produces glucosylceramide (GlcCer) de novo is UDP-glucose ceramide glucosyltransferase (UGCG). UGCG is linked to pro-cancerous processes such as multidrug resistance development and increased proliferation in several cancer type...

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Detalles Bibliográficos
Autores principales: Schömel, Nina, Gruber, Lisa, Alexopoulos, Stephanie J., Trautmann, Sandra, Olzomer, Ellen M., Byrne, Frances L., Hoehn, Kyle L., Gurke, Robert, Thomas, Dominique, Ferreirós, Nerea, Geisslinger, Gerd, Wegner, Marthe-Susanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7234995/
https://www.ncbi.nlm.nih.gov/pubmed/32424263
http://dx.doi.org/10.1038/s41598-020-65182-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7234995/
https://www.ncbi.nlm.nih.gov/pubmed/32424263
http://dx.doi.org/10.1038/s41598-020-65182-y

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