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Tanshinone IIA inhibits oral squamous cell carcinoma via reducing Akt-c-Myc signaling-mediated aerobic glycolysis

Aerobic glycolysis is one of the hallmarks of human cancer cells. Overexpression of hexokinase 2 (HK2) plays a crucial role in the maintaining of unlimited tumor cell growth. In the present study, we found that the oral squamous cell carcinoma (OSCC) cells exhibited an aerobic glycolysis phenotype....

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Detalles Bibliográficos
Autores principales:	Li, Ming, Gao, Feng, Zhao, Qing, Zuo, Huilan, Liu, Wenbin, Li, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235009/ https://www.ncbi.nlm.nih.gov/pubmed/32424132 http://dx.doi.org/10.1038/s41419-020-2579-9

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