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Rapamycin increases the incidence of neuropsychiatric illness in kidney transplant patients through the suppression of neural stem cells

Rapamycin inhibits protein translation in cells, including neural stem cells (NSCs), by suppressing the mechanistic target of rapamycin (mTOR). This drug has been widely used together with calcineurin inhibitors in transplantation patients to prevent graft rejection. Previous studies have reported a...

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Detalles Bibliográficos
Autores principales: Kim, Yangsik, Lee, Jung Sun, Joo, Yeon Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235015/
https://www.ncbi.nlm.nih.gov/pubmed/32424120
http://dx.doi.org/10.1038/s41398-020-0838-2