Drug repurposing of pyrimidine analogs as potent antiviral compounds against human enterovirus A71 infection with potential clinical applications

Enterovirus A71 (EV-A71) is one of the aetiological agents for the hand, foot and mouth disease (HFMD) in young children and a potential cause of neurological complications in afflicted patients. Since its discovery in 1969, there remains no approved antiviral for EV-A71 and other HFMD-causing enter...

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Detalles Bibliográficos
Autores principales: Sun, Jialei, Yogarajah, Thinesshwary, Lee, Regina Ching Hua, Kaur, Parveen, Inoue, Masafumi, Tan, Yong Wah, Chu, Justin Jang Hann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235037/
https://www.ncbi.nlm.nih.gov/pubmed/32424333
http://dx.doi.org/10.1038/s41598-020-65152-4

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