RANK Ligand Helps Immunity to Leishmania major by Skewing M2-Like Into M1 Macrophages

Macrophages host Leishmania major infection, which causes cutaneous Leishmaniasis in humans. In the murine model, resistance to infection depends on the host immunity mediated by CD4 T-cell cytokines and macrophages. In association to other stimuli, the Th1 cytokine IFN-γ induces NO-mediated microbi...

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Detalles Bibliográficos
Autores principales: Rigoni, Thaís S., Vellozo, Natália S., Cabral-Piccin, Mariela, Fabiano-Coelho, Laryssa, Lopes, Ulisses G., Filardy, Alessandra A., DosReis, George A., Lopes, Marcela F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235166/
https://www.ncbi.nlm.nih.gov/pubmed/32477357
http://dx.doi.org/10.3389/fimmu.2020.00886

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235166/
https://www.ncbi.nlm.nih.gov/pubmed/32477357
http://dx.doi.org/10.3389/fimmu.2020.00886

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