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RANK Ligand Helps Immunity to Leishmania major by Skewing M2-Like Into M1 Macrophages
Macrophages host Leishmania major infection, which causes cutaneous Leishmaniasis in humans. In the murine model, resistance to infection depends on the host immunity mediated by CD4 T-cell cytokines and macrophages. In association to other stimuli, the Th1 cytokine IFN-γ induces NO-mediated microbi...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235166/ https://www.ncbi.nlm.nih.gov/pubmed/32477357 http://dx.doi.org/10.3389/fimmu.2020.00886 |