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Characterization and strong risk association of TLR2 del -196 to -174 polymorphism and Helicobacter pylori and their influence on mRNA expression in gastric cancer
BACKGROUND: Toll-like receptor-2 (TLR2) is responsible for recognizing Helicobacter pylori (H. pylori) and activating the immune response. Polymorphisms in TLR2 may modulate gastric carcinogenesis. AIM: To evaluate whether the TLR2 19216T/C (rs3804099) and TLR2 -196 to -174 ins/del (rs111200466) pol...
Autores principales: | Lourenço, Caroline de Matos, Susi, Manoela Dias, do Nascimento, Mariah Cristina Antunes, Serafim Junior, Vilson, Vila, Ana Paula Simedan, Rodrigues-Flemming, Gabriela Helena, Goloni-Bertollo, Eny Maria, Silva, Ana Elizabete, de Oliveira-Cucolo, Juliana Garcia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235183/ https://www.ncbi.nlm.nih.gov/pubmed/32461785 http://dx.doi.org/10.4251/wjgo.v12.i5.535 |
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