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Folic acid attenuates high-fat diet-induced steatohepatitis via deacetylase SIRT1-dependent restoration of PPARα

BACKGROUND: Folic acid has been shown to improve non-alcoholic steatohepatitis (NASH), but its roles in hepatic lipid metabolism, hepatic one-carbon metabolism, and gut microbiota are still unknown. AIM: To demonstrate the role of folic acid in lipid metabolism and gut microbiota in NASH. METHODS: T...

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Detalles Bibliográficos
Autores principales: Xin, Feng-Zhi, Zhao, Ze-Hua, Zhang, Rui-Nan, Pan, Qin, Gong, Zi-Zhen, Sun, Chao, Fan, Jian-Gao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235203/
https://www.ncbi.nlm.nih.gov/pubmed/32476787
http://dx.doi.org/10.3748/wjg.v26.i18.2203