The IL-33-induced p38-/JNK1/2-TNFα axis is antagonized by activation of β-adrenergic-receptors in dendritic cells

IL-33, an IL-1 cytokine superfamily member, induces the activation of the canonical NF-κB signaling, and of Mitogen Activated Protein Kinases (MAPKs). In dendritic cells (DCs) IL-33 induces the production of IL-6, IL-13 and TNFα. Thereby, the production of IL-6 depends on RelA whereas the production...

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Detalles Bibliográficos
Autores principales: Helbig, Christiane, Weber, Franziska, Andreas, Nico, Herdegen, Thomas, Gaestel, Matthias, Kamradt, Thomas, Drube, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235212/
https://www.ncbi.nlm.nih.gov/pubmed/32424229
http://dx.doi.org/10.1038/s41598-020-65072-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235212/
https://www.ncbi.nlm.nih.gov/pubmed/32424229
http://dx.doi.org/10.1038/s41598-020-65072-3

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