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Visualization of PS/γ-Secretase Activity in Living Cells

A change in Presenilin (PS)/γ-secretase activity is linked to essential biological events as well as to the progression of many diseases. However, not much is known about how PS/γ-secretase activity is spatiotemporally regulated in cells. One of the limitations is lack of tools to directly monitor d...

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Detalles Bibliográficos
Autores principales: Maesako, Masato, Sekula, Nicole M., Aristarkhova, Anna, Feschenko, Polina, Anderson, Lauren C., Berezovska, Oksana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235286/
https://www.ncbi.nlm.nih.gov/pubmed/32438286
http://dx.doi.org/10.1016/j.isci.2020.101139