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Visualization of PS/γ-Secretase Activity in Living Cells
A change in Presenilin (PS)/γ-secretase activity is linked to essential biological events as well as to the progression of many diseases. However, not much is known about how PS/γ-secretase activity is spatiotemporally regulated in cells. One of the limitations is lack of tools to directly monitor d...
Autores principales: | Maesako, Masato, Sekula, Nicole M., Aristarkhova, Anna, Feschenko, Polina, Anderson, Lauren C., Berezovska, Oksana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235286/ https://www.ncbi.nlm.nih.gov/pubmed/32438286 http://dx.doi.org/10.1016/j.isci.2020.101139 |
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