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Preschool Wheezing: Trajectories and Long-Term Treatment

Wheezing is very common in infancy affecting one in three children during the first 3 years of life. Several wheeze phenotypes have been identified and most rely on temporal pattern of symptoms. Assessing the risk of asthma development is difficult. Factors predisposing to onset and persistence of w...

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Autores principales: Fainardi, Valentina, Santoro, Angelica, Caffarelli, Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235303/
https://www.ncbi.nlm.nih.gov/pubmed/32478019
http://dx.doi.org/10.3389/fped.2020.00240
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author Fainardi, Valentina
Santoro, Angelica
Caffarelli, Carlo
author_facet Fainardi, Valentina
Santoro, Angelica
Caffarelli, Carlo
author_sort Fainardi, Valentina
collection PubMed
description Wheezing is very common in infancy affecting one in three children during the first 3 years of life. Several wheeze phenotypes have been identified and most rely on temporal pattern of symptoms. Assessing the risk of asthma development is difficult. Factors predisposing to onset and persistence of wheezing such as breastfeeding, atopy, indoor allergen exposure, environmental tobacco smoke and viral infections are analyzed. Inhaled corticosteroids are recommended as first choice of controller treatment in all preschool children irrespective of phenotype, but they are particularly beneficial in terms of fewer exacerbations in atopic children. Other therapeutic options include the addition of montelukast or the intermittent use of inhaled corticosteroids. Overuse of inhaled steroids must be avoided. Therefore, adherence to treatment and correct administration of the medications need to be checked at every visit.
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spelling pubmed-72353032020-05-29 Preschool Wheezing: Trajectories and Long-Term Treatment Fainardi, Valentina Santoro, Angelica Caffarelli, Carlo Front Pediatr Pediatrics Wheezing is very common in infancy affecting one in three children during the first 3 years of life. Several wheeze phenotypes have been identified and most rely on temporal pattern of symptoms. Assessing the risk of asthma development is difficult. Factors predisposing to onset and persistence of wheezing such as breastfeeding, atopy, indoor allergen exposure, environmental tobacco smoke and viral infections are analyzed. Inhaled corticosteroids are recommended as first choice of controller treatment in all preschool children irrespective of phenotype, but they are particularly beneficial in terms of fewer exacerbations in atopic children. Other therapeutic options include the addition of montelukast or the intermittent use of inhaled corticosteroids. Overuse of inhaled steroids must be avoided. Therefore, adherence to treatment and correct administration of the medications need to be checked at every visit. Frontiers Media S.A. 2020-05-12 /pmc/articles/PMC7235303/ /pubmed/32478019 http://dx.doi.org/10.3389/fped.2020.00240 Text en Copyright © 2020 Fainardi, Santoro and Caffarelli. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pediatrics
Fainardi, Valentina
Santoro, Angelica
Caffarelli, Carlo
Preschool Wheezing: Trajectories and Long-Term Treatment
title Preschool Wheezing: Trajectories and Long-Term Treatment
title_full Preschool Wheezing: Trajectories and Long-Term Treatment
title_fullStr Preschool Wheezing: Trajectories and Long-Term Treatment
title_full_unstemmed Preschool Wheezing: Trajectories and Long-Term Treatment
title_short Preschool Wheezing: Trajectories and Long-Term Treatment
title_sort preschool wheezing: trajectories and long-term treatment
topic Pediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235303/
https://www.ncbi.nlm.nih.gov/pubmed/32478019
http://dx.doi.org/10.3389/fped.2020.00240
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