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Preschool Wheezing: Trajectories and Long-Term Treatment
Wheezing is very common in infancy affecting one in three children during the first 3 years of life. Several wheeze phenotypes have been identified and most rely on temporal pattern of symptoms. Assessing the risk of asthma development is difficult. Factors predisposing to onset and persistence of w...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235303/ https://www.ncbi.nlm.nih.gov/pubmed/32478019 http://dx.doi.org/10.3389/fped.2020.00240 |
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author | Fainardi, Valentina Santoro, Angelica Caffarelli, Carlo |
author_facet | Fainardi, Valentina Santoro, Angelica Caffarelli, Carlo |
author_sort | Fainardi, Valentina |
collection | PubMed |
description | Wheezing is very common in infancy affecting one in three children during the first 3 years of life. Several wheeze phenotypes have been identified and most rely on temporal pattern of symptoms. Assessing the risk of asthma development is difficult. Factors predisposing to onset and persistence of wheezing such as breastfeeding, atopy, indoor allergen exposure, environmental tobacco smoke and viral infections are analyzed. Inhaled corticosteroids are recommended as first choice of controller treatment in all preschool children irrespective of phenotype, but they are particularly beneficial in terms of fewer exacerbations in atopic children. Other therapeutic options include the addition of montelukast or the intermittent use of inhaled corticosteroids. Overuse of inhaled steroids must be avoided. Therefore, adherence to treatment and correct administration of the medications need to be checked at every visit. |
format | Online Article Text |
id | pubmed-7235303 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-72353032020-05-29 Preschool Wheezing: Trajectories and Long-Term Treatment Fainardi, Valentina Santoro, Angelica Caffarelli, Carlo Front Pediatr Pediatrics Wheezing is very common in infancy affecting one in three children during the first 3 years of life. Several wheeze phenotypes have been identified and most rely on temporal pattern of symptoms. Assessing the risk of asthma development is difficult. Factors predisposing to onset and persistence of wheezing such as breastfeeding, atopy, indoor allergen exposure, environmental tobacco smoke and viral infections are analyzed. Inhaled corticosteroids are recommended as first choice of controller treatment in all preschool children irrespective of phenotype, but they are particularly beneficial in terms of fewer exacerbations in atopic children. Other therapeutic options include the addition of montelukast or the intermittent use of inhaled corticosteroids. Overuse of inhaled steroids must be avoided. Therefore, adherence to treatment and correct administration of the medications need to be checked at every visit. Frontiers Media S.A. 2020-05-12 /pmc/articles/PMC7235303/ /pubmed/32478019 http://dx.doi.org/10.3389/fped.2020.00240 Text en Copyright © 2020 Fainardi, Santoro and Caffarelli. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Pediatrics Fainardi, Valentina Santoro, Angelica Caffarelli, Carlo Preschool Wheezing: Trajectories and Long-Term Treatment |
title | Preschool Wheezing: Trajectories and Long-Term Treatment |
title_full | Preschool Wheezing: Trajectories and Long-Term Treatment |
title_fullStr | Preschool Wheezing: Trajectories and Long-Term Treatment |
title_full_unstemmed | Preschool Wheezing: Trajectories and Long-Term Treatment |
title_short | Preschool Wheezing: Trajectories and Long-Term Treatment |
title_sort | preschool wheezing: trajectories and long-term treatment |
topic | Pediatrics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235303/ https://www.ncbi.nlm.nih.gov/pubmed/32478019 http://dx.doi.org/10.3389/fped.2020.00240 |
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