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Recent Advances in NAMPT Inhibitors: A Novel Immunotherapic Strategy

Nicotinamide adenine dinucleotide (NAD) is a cofactor of many enzymatic reactions as well as being a substrate for a number of NAD-consuming enzymes (e.g., PARPS, sirtuins, etc). NAD can be synthesized de novo starting from tryptophan, nicotinamide, nicotinic acid, or nicotinamide riboside from the...

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Detalles Bibliográficos
Autores principales: Galli, Ubaldina, Colombo, Giorgia, Travelli, Cristina, Tron, Gian Cesare, Genazzani, Armando A., Grolla, Ambra A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235340/
https://www.ncbi.nlm.nih.gov/pubmed/32477131
http://dx.doi.org/10.3389/fphar.2020.00656