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Understanding Non-Mendelian Genetic Risk

This opinion paper highlights strategies for a better understanding of non-Mendelian genetic risk that was revealed by genome-wide association studies (GWAS) of complex diseases. The genetic risk resides predominantly in non-coding regulatory DNA, such as in enhancers. The identification of mechanis...

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Detalles Bibliográficos
Autor principal:	Coetzee, Gerhard A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bentham Science Publishers 2019
Materias:	Genomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235392/ https://www.ncbi.nlm.nih.gov/pubmed/32476988 http://dx.doi.org/10.2174/1389202920666191018085511

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