Cargando…
KLRG1 and CD103 Expressions Define Distinct Intestinal Tissue-Resident Memory CD8 T Cell Subsets Modulated in Crohn's Disease
Intestinal tissue-resident memory CD8 T cells (Trm) are non-recirculating effector cells ideally positioned to detect and react to microbial infections in the gut mucosa. There is an emerging understanding of Trm cell differentiation and functions, but their implication in inflammatory bowel disease...
Autores principales: | Bottois, Hugo, Ngollo, Marjolaine, Hammoudi, Nassim, Courau, Tristan, Bonnereau, Julie, Chardiny, Victor, Grand, Céline, Gergaud, Brice, Allez, Matthieu, Le Bourhis, Lionel |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235448/ https://www.ncbi.nlm.nih.gov/pubmed/32477365 http://dx.doi.org/10.3389/fimmu.2020.00896 |
Ejemplares similares
-
Autologous organoid co-culture model reveals T cell-driven epithelial cell death in Crohn’s Disease
por: Hammoudi, Nassim, et al.
Publicado: (2022) -
Cocultures of human colorectal tumor spheroids with immune cells reveal the therapeutic potential of MICA/B and NKG2A targeting for cancer treatment
por: Courau, Tristan, et al.
Publicado: (2019) -
Expression of KLRG1 and CD127 defines distinct CD8(+) subsets that differentially impact patient outcome in follicular lymphoma
por: Wu, Hongyan, et al.
Publicado: (2021) -
KLRG1 marks tumor-infiltrating CD4 T cell subsets associated with tumor progression and immunotherapy response
por: Ager, Casey R, et al.
Publicado: (2023) -
Intestinal CD103(+)CD4(+) and CD103(+)CD8(+) T-Cell Subsets in the Gut of Inflammatory Bowel Disease Patients at Diagnosis and During Follow-up
por: Roosenboom, Britt, et al.
Publicado: (2019)