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Inferior vena cava resection and reconstruction with a peritoneal patch for a leiomyosarcoma: A case report

INTRODUCTION: Leiomyosarcomas (LMs) of the inferior vena cava (IVC) are very rare neoplasms seldom reported in the literature. The majority of patients does not present with specific abdominal pain and IVC LMs are used to become symptomatic with the increase of tumor volume. The role of chemotherapy...

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Autores principales: Risaliti, Matteo, Fortuna, Laura, Bartolini, Ilenia, Taddei, Antonio, Muiesan, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235614/
https://www.ncbi.nlm.nih.gov/pubmed/32438334
http://dx.doi.org/10.1016/j.ijscr.2020.04.031
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author Risaliti, Matteo
Fortuna, Laura
Bartolini, Ilenia
Taddei, Antonio
Muiesan, Paolo
author_facet Risaliti, Matteo
Fortuna, Laura
Bartolini, Ilenia
Taddei, Antonio
Muiesan, Paolo
author_sort Risaliti, Matteo
collection PubMed
description INTRODUCTION: Leiomyosarcomas (LMs) of the inferior vena cava (IVC) are very rare neoplasms seldom reported in the literature. The majority of patients does not present with specific abdominal pain and IVC LMs are used to become symptomatic with the increase of tumor volume. The role of chemotherapy or radiotherapy is not yet defined and surgical resection seems to be the only chance to improve survival rates. PRESENTATION OF CASE: We present a case of a 58-year-old female with a recent diagnosis of IVC LM who underwent surgery with a partial resection of the anterior wall of the vein using a lateral and partial vein clamping. The primary repair of the defect could result in stricture of the vein, so a parietal peritoneum patch was used for the vein reconstruction. The postoperative course was uneventful. DISCUSSION: Actual evidence suggests that vascular sarcomas have limited responsiveness to cytotoxic chemotherapy and chemoradiotherapy, so surgery is the treatment of choice. Major surgery entailing multivisceral and complex vascular resection is usually necessary to achieve negative margins and accurate vascular reconstruction techniques are mandatory to avoid serious circulatory complications. Different kinds of graft (biological or synthetics) are available for the reconstruction, with intrinsic advantages and limitations. The use of peritoneal patches seems a valid and cheap option for vascular reconstruction and it is gaining great attention in recent years. CONCLUSION: This case demonstrates that peritoneal graft could be a safe option to manage IVC defects in expert hands. A brief review of literature is also included.
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spelling pubmed-72356142020-05-22 Inferior vena cava resection and reconstruction with a peritoneal patch for a leiomyosarcoma: A case report Risaliti, Matteo Fortuna, Laura Bartolini, Ilenia Taddei, Antonio Muiesan, Paolo Int J Surg Case Rep Article INTRODUCTION: Leiomyosarcomas (LMs) of the inferior vena cava (IVC) are very rare neoplasms seldom reported in the literature. The majority of patients does not present with specific abdominal pain and IVC LMs are used to become symptomatic with the increase of tumor volume. The role of chemotherapy or radiotherapy is not yet defined and surgical resection seems to be the only chance to improve survival rates. PRESENTATION OF CASE: We present a case of a 58-year-old female with a recent diagnosis of IVC LM who underwent surgery with a partial resection of the anterior wall of the vein using a lateral and partial vein clamping. The primary repair of the defect could result in stricture of the vein, so a parietal peritoneum patch was used for the vein reconstruction. The postoperative course was uneventful. DISCUSSION: Actual evidence suggests that vascular sarcomas have limited responsiveness to cytotoxic chemotherapy and chemoradiotherapy, so surgery is the treatment of choice. Major surgery entailing multivisceral and complex vascular resection is usually necessary to achieve negative margins and accurate vascular reconstruction techniques are mandatory to avoid serious circulatory complications. Different kinds of graft (biological or synthetics) are available for the reconstruction, with intrinsic advantages and limitations. The use of peritoneal patches seems a valid and cheap option for vascular reconstruction and it is gaining great attention in recent years. CONCLUSION: This case demonstrates that peritoneal graft could be a safe option to manage IVC defects in expert hands. A brief review of literature is also included. Elsevier 2020-05-08 /pmc/articles/PMC7235614/ /pubmed/32438334 http://dx.doi.org/10.1016/j.ijscr.2020.04.031 Text en © 2020 The Author(s) http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Risaliti, Matteo
Fortuna, Laura
Bartolini, Ilenia
Taddei, Antonio
Muiesan, Paolo
Inferior vena cava resection and reconstruction with a peritoneal patch for a leiomyosarcoma: A case report
title Inferior vena cava resection and reconstruction with a peritoneal patch for a leiomyosarcoma: A case report
title_full Inferior vena cava resection and reconstruction with a peritoneal patch for a leiomyosarcoma: A case report
title_fullStr Inferior vena cava resection and reconstruction with a peritoneal patch for a leiomyosarcoma: A case report
title_full_unstemmed Inferior vena cava resection and reconstruction with a peritoneal patch for a leiomyosarcoma: A case report
title_short Inferior vena cava resection and reconstruction with a peritoneal patch for a leiomyosarcoma: A case report
title_sort inferior vena cava resection and reconstruction with a peritoneal patch for a leiomyosarcoma: a case report
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235614/
https://www.ncbi.nlm.nih.gov/pubmed/32438334
http://dx.doi.org/10.1016/j.ijscr.2020.04.031
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