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Adipocyte-specific Beclin1 deletion impairs lipolysis and mitochondrial integrity in adipose tissue

OBJECTIVE: Beclin1 is a core molecule of the macroautophagy machinery. Although dysregulation of macroautophagy is known to be involved in metabolic disorders, the function of Beclin1 in adipocyte metabolism has not been investigated. In the present study, we aimed to study the role of Beclin1 in li...

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Detalles Bibliográficos
Autores principales: Son, Yeonho, Cho, Yoon Keun, Saha, Abhirup, Kwon, Hyun-Jung, Park, Ji-Hyun, Kim, Minsu, Jung, Young-Suk, Kim, Sang-Nam, Choi, Cheoljun, Seong, Je-Kyung, Burl, Rayanne B., Granneman, James G., Lee, Yun-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235646/
https://www.ncbi.nlm.nih.gov/pubmed/32344065
http://dx.doi.org/10.1016/j.molmet.2020.101005