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Adipocyte-specific Beclin1 deletion impairs lipolysis and mitochondrial integrity in adipose tissue
OBJECTIVE: Beclin1 is a core molecule of the macroautophagy machinery. Although dysregulation of macroautophagy is known to be involved in metabolic disorders, the function of Beclin1 in adipocyte metabolism has not been investigated. In the present study, we aimed to study the role of Beclin1 in li...
Autores principales: | Son, Yeonho, Cho, Yoon Keun, Saha, Abhirup, Kwon, Hyun-Jung, Park, Ji-Hyun, Kim, Minsu, Jung, Young-Suk, Kim, Sang-Nam, Choi, Cheoljun, Seong, Je-Kyung, Burl, Rayanne B., Granneman, James G., Lee, Yun-Hee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235646/ https://www.ncbi.nlm.nih.gov/pubmed/32344065 http://dx.doi.org/10.1016/j.molmet.2020.101005 |
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