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Apoptosis signal-regulating kinase 1 inhibition in in vivo and in vitro models of pulmonary hypertension
Pulmonary arterial hypertension, group 1 of the pulmonary hypertension disease family, involves pulmonary vascular remodelling, right ventricular dysfunction and cardiac failure. Oxidative stress, through activation of mitogen-activated protein kinases is implicated in these changes. Inhibition of a...
Autores principales: | Wilson, Kathryn S., Buist, Hanna, Suveizdyte, Kornelija, Liles, John T., Budas, Grant R., Hughes, Colin, MacLean, Margaret R., Johnson, Martin, Church, Alistair C., Peacock, Andrew J., Welsh, David J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235684/ https://www.ncbi.nlm.nih.gov/pubmed/32523684 http://dx.doi.org/10.1177/2045894020922810 |
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