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Spun Biotextiles in Tissue Engineering and Biomolecules Delivery Systems

Nowadays, tissue engineering is described as an interdisciplinary field that combines engineering principles and life sciences to generate implantable devices to repair, restore and/or improve functions of injured tissues. Such devices are designed to induce the interaction and integration of tissue...

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Detalles Bibliográficos
Autores principales: Miranda, Catarina S., Ribeiro, Ana R. M., Homem, Natália C., Felgueiras, Helena P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235791/
https://www.ncbi.nlm.nih.gov/pubmed/32290536
http://dx.doi.org/10.3390/antibiotics9040174
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author Miranda, Catarina S.
Ribeiro, Ana R. M.
Homem, Natália C.
Felgueiras, Helena P.
author_facet Miranda, Catarina S.
Ribeiro, Ana R. M.
Homem, Natália C.
Felgueiras, Helena P.
author_sort Miranda, Catarina S.
collection PubMed
description Nowadays, tissue engineering is described as an interdisciplinary field that combines engineering principles and life sciences to generate implantable devices to repair, restore and/or improve functions of injured tissues. Such devices are designed to induce the interaction and integration of tissue and cells within the implantable matrices and are manufactured to meet the appropriate physical, mechanical and physiological local demands. Biodegradable constructs based on polymeric fibers are desirable for tissue engineering due to their large surface area, interconnectivity, open pore structure, and controlled mechanical strength. Additionally, biodegradable constructs are also very sought-out for biomolecule delivery systems with a target-directed action. In the present review, we explore the properties of some of the most common biodegradable polymers used in tissue engineering applications and biomolecule delivery systems and highlight their most important uses.
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spelling pubmed-72357912020-05-22 Spun Biotextiles in Tissue Engineering and Biomolecules Delivery Systems Miranda, Catarina S. Ribeiro, Ana R. M. Homem, Natália C. Felgueiras, Helena P. Antibiotics (Basel) Review Nowadays, tissue engineering is described as an interdisciplinary field that combines engineering principles and life sciences to generate implantable devices to repair, restore and/or improve functions of injured tissues. Such devices are designed to induce the interaction and integration of tissue and cells within the implantable matrices and are manufactured to meet the appropriate physical, mechanical and physiological local demands. Biodegradable constructs based on polymeric fibers are desirable for tissue engineering due to their large surface area, interconnectivity, open pore structure, and controlled mechanical strength. Additionally, biodegradable constructs are also very sought-out for biomolecule delivery systems with a target-directed action. In the present review, we explore the properties of some of the most common biodegradable polymers used in tissue engineering applications and biomolecule delivery systems and highlight their most important uses. MDPI 2020-04-12 /pmc/articles/PMC7235791/ /pubmed/32290536 http://dx.doi.org/10.3390/antibiotics9040174 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Miranda, Catarina S.
Ribeiro, Ana R. M.
Homem, Natália C.
Felgueiras, Helena P.
Spun Biotextiles in Tissue Engineering and Biomolecules Delivery Systems
title Spun Biotextiles in Tissue Engineering and Biomolecules Delivery Systems
title_full Spun Biotextiles in Tissue Engineering and Biomolecules Delivery Systems
title_fullStr Spun Biotextiles in Tissue Engineering and Biomolecules Delivery Systems
title_full_unstemmed Spun Biotextiles in Tissue Engineering and Biomolecules Delivery Systems
title_short Spun Biotextiles in Tissue Engineering and Biomolecules Delivery Systems
title_sort spun biotextiles in tissue engineering and biomolecules delivery systems
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235791/
https://www.ncbi.nlm.nih.gov/pubmed/32290536
http://dx.doi.org/10.3390/antibiotics9040174
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