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Factors Influencing the Prevalence of Resistance-Associated Substitutions in NS5A Protein in Treatment-Naive Patients with Chronic Hepatitis C

Direct-acting antivirals (DAAs) revolutionized treatment of hepatitis C virus (HCV) infection. Resistance-associated substitutions (RASs) present at the baseline impair response to DAA due to rapid selection of resistant HCV strains. NS5A is indispensable target of the current DAA treatment regimens...

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Detalles Bibliográficos
Autores principales:	Kyuregyan, Karen K., Kichatova, Vera S., Karlsen, Anastasiya A., Isaeva, Olga V., Solonin, Sergei A., Petkov, Stefan, Nielsen, Morten, Isaguliants, Maria G., Mikhailov, Mikhail I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235841/ https://www.ncbi.nlm.nih.gov/pubmed/32272736 http://dx.doi.org/10.3390/biomedicines8040080

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