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Human Clinical Relevance of the Porcine Model of Pseudoallergic Infusion Reactions

Pigs provide a highly sensitive animal model for pseudoallergic infusion reactions, which are mild-to-severe hypersensitivity reactions (HSRs) that arise following intravenous administration of certain nanoparticulate drugs (nanomedicines) and other macromolecular structures. This model has been use...

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Detalles Bibliográficos
Autores principales: Szebeni, János, Bawa, Raj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235862/
https://www.ncbi.nlm.nih.gov/pubmed/32276476
http://dx.doi.org/10.3390/biomedicines8040082