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Estrogen Signaling Induces Mitochondrial Dysfunction-Associated Autophagy and Senescence in Breast Cancer Cells

Previous work has shown that although estrogen (E2) disrupts cellular iron metabolism and induces oxidative stress in breast and ovarian cancer cells, it fails to induce apoptosis. However, E2 treatment was reported to enhance the apoptotic effects of doxorubicin in cancer cells. This suggests that...

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Detalles Bibliográficos
Autores principales: Bajbouj, Khuloud, Shafarin, Jasmin, Taneera, Jalal, Hamad, Mawieh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235898/
https://www.ncbi.nlm.nih.gov/pubmed/32244623
http://dx.doi.org/10.3390/biology9040068