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Dried Blood Spot in Laboratory: Directions and Prospects
Over the past few years, dried blood spot (DBS) technology has become a convenient tool in both qualitative and quantitative biological analysis. DBS technology consists of a membrane carrier (MC) on the surface of which a biomaterial sample becomes absorbed. Modern analytical, immunological or geno...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235996/ https://www.ncbi.nlm.nih.gov/pubmed/32340321 http://dx.doi.org/10.3390/diagnostics10040248 |
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author | Malsagova, Kristina Kopylov, Artur Stepanov, Alexander Butkova, Tatyana Izotov, Alexander Kaysheva, Anna |
author_facet | Malsagova, Kristina Kopylov, Artur Stepanov, Alexander Butkova, Tatyana Izotov, Alexander Kaysheva, Anna |
author_sort | Malsagova, Kristina |
collection | PubMed |
description | Over the past few years, dried blood spot (DBS) technology has become a convenient tool in both qualitative and quantitative biological analysis. DBS technology consists of a membrane carrier (MC) on the surface of which a biomaterial sample becomes absorbed. Modern analytical, immunological or genomic methods can be employed for analysis after drying the sample. DBS has been described as the most appropriate method for biomaterial sampling due to specific associated inherent advantages, including the small volumes of biomaterials required, the absence of a need for special conditions for samples’ storage and transportation, improved stability of analytes and reduced risk of infection resulting from contaminated samples. This review illustrates information on the current state of DBS technology, which can be useful and helpful for biomedical researchers. The prospects of using this technology to assess the metabolomic profile, assessment, diagnosis of communicable diseases are demonstrated. |
format | Online Article Text |
id | pubmed-7235996 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-72359962020-05-28 Dried Blood Spot in Laboratory: Directions and Prospects Malsagova, Kristina Kopylov, Artur Stepanov, Alexander Butkova, Tatyana Izotov, Alexander Kaysheva, Anna Diagnostics (Basel) Review Over the past few years, dried blood spot (DBS) technology has become a convenient tool in both qualitative and quantitative biological analysis. DBS technology consists of a membrane carrier (MC) on the surface of which a biomaterial sample becomes absorbed. Modern analytical, immunological or genomic methods can be employed for analysis after drying the sample. DBS has been described as the most appropriate method for biomaterial sampling due to specific associated inherent advantages, including the small volumes of biomaterials required, the absence of a need for special conditions for samples’ storage and transportation, improved stability of analytes and reduced risk of infection resulting from contaminated samples. This review illustrates information on the current state of DBS technology, which can be useful and helpful for biomedical researchers. The prospects of using this technology to assess the metabolomic profile, assessment, diagnosis of communicable diseases are demonstrated. MDPI 2020-04-23 /pmc/articles/PMC7235996/ /pubmed/32340321 http://dx.doi.org/10.3390/diagnostics10040248 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Malsagova, Kristina Kopylov, Artur Stepanov, Alexander Butkova, Tatyana Izotov, Alexander Kaysheva, Anna Dried Blood Spot in Laboratory: Directions and Prospects |
title | Dried Blood Spot in Laboratory: Directions and Prospects |
title_full | Dried Blood Spot in Laboratory: Directions and Prospects |
title_fullStr | Dried Blood Spot in Laboratory: Directions and Prospects |
title_full_unstemmed | Dried Blood Spot in Laboratory: Directions and Prospects |
title_short | Dried Blood Spot in Laboratory: Directions and Prospects |
title_sort | dried blood spot in laboratory: directions and prospects |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235996/ https://www.ncbi.nlm.nih.gov/pubmed/32340321 http://dx.doi.org/10.3390/diagnostics10040248 |
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