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Dried Blood Spot in Laboratory: Directions and Prospects

Over the past few years, dried blood spot (DBS) technology has become a convenient tool in both qualitative and quantitative biological analysis. DBS technology consists of a membrane carrier (MC) on the surface of which a biomaterial sample becomes absorbed. Modern analytical, immunological or geno...

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Autores principales: Malsagova, Kristina, Kopylov, Artur, Stepanov, Alexander, Butkova, Tatyana, Izotov, Alexander, Kaysheva, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235996/
https://www.ncbi.nlm.nih.gov/pubmed/32340321
http://dx.doi.org/10.3390/diagnostics10040248
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author Malsagova, Kristina
Kopylov, Artur
Stepanov, Alexander
Butkova, Tatyana
Izotov, Alexander
Kaysheva, Anna
author_facet Malsagova, Kristina
Kopylov, Artur
Stepanov, Alexander
Butkova, Tatyana
Izotov, Alexander
Kaysheva, Anna
author_sort Malsagova, Kristina
collection PubMed
description Over the past few years, dried blood spot (DBS) technology has become a convenient tool in both qualitative and quantitative biological analysis. DBS technology consists of a membrane carrier (MC) on the surface of which a biomaterial sample becomes absorbed. Modern analytical, immunological or genomic methods can be employed for analysis after drying the sample. DBS has been described as the most appropriate method for biomaterial sampling due to specific associated inherent advantages, including the small volumes of biomaterials required, the absence of a need for special conditions for samples’ storage and transportation, improved stability of analytes and reduced risk of infection resulting from contaminated samples. This review illustrates information on the current state of DBS technology, which can be useful and helpful for biomedical researchers. The prospects of using this technology to assess the metabolomic profile, assessment, diagnosis of communicable diseases are demonstrated.
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spelling pubmed-72359962020-05-28 Dried Blood Spot in Laboratory: Directions and Prospects Malsagova, Kristina Kopylov, Artur Stepanov, Alexander Butkova, Tatyana Izotov, Alexander Kaysheva, Anna Diagnostics (Basel) Review Over the past few years, dried blood spot (DBS) technology has become a convenient tool in both qualitative and quantitative biological analysis. DBS technology consists of a membrane carrier (MC) on the surface of which a biomaterial sample becomes absorbed. Modern analytical, immunological or genomic methods can be employed for analysis after drying the sample. DBS has been described as the most appropriate method for biomaterial sampling due to specific associated inherent advantages, including the small volumes of biomaterials required, the absence of a need for special conditions for samples’ storage and transportation, improved stability of analytes and reduced risk of infection resulting from contaminated samples. This review illustrates information on the current state of DBS technology, which can be useful and helpful for biomedical researchers. The prospects of using this technology to assess the metabolomic profile, assessment, diagnosis of communicable diseases are demonstrated. MDPI 2020-04-23 /pmc/articles/PMC7235996/ /pubmed/32340321 http://dx.doi.org/10.3390/diagnostics10040248 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Malsagova, Kristina
Kopylov, Artur
Stepanov, Alexander
Butkova, Tatyana
Izotov, Alexander
Kaysheva, Anna
Dried Blood Spot in Laboratory: Directions and Prospects
title Dried Blood Spot in Laboratory: Directions and Prospects
title_full Dried Blood Spot in Laboratory: Directions and Prospects
title_fullStr Dried Blood Spot in Laboratory: Directions and Prospects
title_full_unstemmed Dried Blood Spot in Laboratory: Directions and Prospects
title_short Dried Blood Spot in Laboratory: Directions and Prospects
title_sort dried blood spot in laboratory: directions and prospects
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235996/
https://www.ncbi.nlm.nih.gov/pubmed/32340321
http://dx.doi.org/10.3390/diagnostics10040248
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