Cargando…

Knockdown of N-Acetylglucosaminyltransferase-II Reduces Matrix Metalloproteinase 2 Activity and Suppresses Tumorigenicity in Neuroblastoma Cell Line

Neuroblastoma (NB) development and progression are accompanied by changes in N-glycans attached to proteins. Here, we investigated the role of N-acetylglucosaminyltransferase-II (GnTII, MGAT2) protein substrates in neuroblastoma (NB) cells. MGAT2 was silenced in human BE(2)-C NB (HuNB) cells to gene...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hall, M. Kristen, Whitman, Austin A., Weidner, Douglas A., Schwalbe, Ruth A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236022/ https://www.ncbi.nlm.nih.gov/pubmed/32260356 http://dx.doi.org/10.3390/biology9040071

Ejemplares similares

Functional analysis of N-acetylglucosaminyltransferase-I knockdown in 2D and 3D neuroblastoma cell cultures
por: Hall, M. Kristen, et al.
Publicado: (2021)

Reduction in N-Acetylglucosaminyltransferase-I Activity Decreases Survivability and Delays Development of Zebrafish
por: Hall, M. Kristen, et al.
Publicado: (2023)

Lack of complex type N-glycans lessens aberrant neuronal properties
por: Hall, M. Kristen, et al.
Publicado: (2018)

Predominant Expression of Hybrid N-Glycans Has Distinct Cellular Roles Relative to Complex and Oligomannose N-Glycans
por: Hall, M. Kristen, et al.
Publicado: (2016)

Membrane-type 1 matrix metalloproteinase-mediated progelatinase A activation in non-tumorigenic and tumorigenic humaneratinocytes
por: Baumann, P, et al.
Publicado: (2000)

Cell surface N-glycans influence the level of functional E-cadherin at the cell–cell border
por: Hall, M. Kristen, et al.
Publicado: (2014)

Tissue Inhibitor of Matrix Metalloproteinases-1 Knockdown Suppresses the Proliferation of Human Adipose-Derived Stem Cells
por: Zhang, Peihua, et al.
Publicado: (2016)

Kinetochore-associated protein 1 promotes the invasion and tumorigenicity of cervical cancer cells via matrix metalloproteinase-2 and matrix metalloproteinase-9
por: Wang, Caimei, et al.
Publicado: (2022)

Complex N-Glycans Influence the Spatial Arrangement of Voltage Gated Potassium Channels in Membranes of Neuronal-Derived Cells
por: Hall, M. Kristen, et al.
Publicado: (2015)

miRNA-337-3p suppresses neuroblastoma progression by repressing the transcription of matrix metalloproteinase 14
por: Xiang, Xuan, et al.
Publicado: (2015)

Knockdown of Pentraxin 3 suppresses tumorigenicity and metastasis of human cervical cancer cells
por: Ying, Tsung-Ho, et al.
Publicado: (2016)

Biomarkers for Predicting the Occurrence and Progression of Atrial Fibrillation: Soluble Suppression of Tumorigenicity 2 Protein and Tissue Inhibitor of Matrix Metalloproteinase-1
por: Sun, Wei-Ping, et al.
Publicado: (2022)

Promising Noninvasive Cellular Phenotype in Prostate Cancer Cells Knockdown of Matrix Metalloproteinase 9
por: Gupta, Aditi, et al.
Publicado: (2013)

Glycan Structures Contain Information for the Spatial Arrangement of Glycoproteins in the Plasma Membrane
por: Hall, M. Kristen, et al.
Publicado: (2013)

Structure and mechanism of cancer-associated N-acetylglucosaminyltransferase-V
por: Nagae, Masamichi, et al.
Publicado: (2018)

Cryostorage of unstable N-acetylglucosaminyltransferase-V by synthetic zwitterions
por: Hirata, Tetsuya, et al.
Publicado: (2022)

Matrix Metalloproteinase 2 Knockdown Suppresses the Proliferation of HepG2 and Huh7 Cells and Enhances the Cisplatin Effect
por: Liu, Jiangwei, et al.
Publicado: (2019)

Importance of Glycosylation on Function of a Potassium Channel in Neuroblastoma Cells
por: Hall, M. K., et al.
Publicado: (2011)

Effects of Surgery Combined with Different Chemotherapy on Matrix Metalloproteinase-9 and Tissue Inhibitors of Metalloproteinase-1 in Children with Neuroblastoma
por: Qi, Zilong, et al.
Publicado: (2022)

Membrane Distribution and Activity of a Neuronal Voltage-Gated K+ Channel is Modified by Replacement of Complex Type N-Glycans with Hybrid Type
por: Hall, M Kristen, et al.
Publicado: (2017)

Limited N-Glycan Processing Impacts Chaperone Expression Patterns, Cell Growth and Cell Invasiveness in Neuroblastoma
por: Hall, M. Kristen, et al.
Publicado: (2023)

Expression of N-acetylglucosaminyltransferase V in endometrial cancer correlates with poor prognosis
por: Yamamoto, E, et al.
Publicado: (2007)

High expression of N-acetylglucosaminyltransferase IVa promotes invasion of choriocarcinoma
por: Niimi, K, et al.
Publicado: (2012)

Tumor suppression by control of matrix metalloproteinase recycling
por: Sneeggen, Marte, et al.
Publicado: (2019)

Compromised N-Glycosylation Processing of Kv3.1b Correlates with Perturbed Motor Neuron Structure and Locomotor Activity
por: Issa, Fadi A., et al.
Publicado: (2021)

Identification of membrane-type 1 matrix metalloproteinase tyrosine phosphorylation in association with neuroblastoma progression
por: Nyalendo, Carine, et al.
Publicado: (2009)

Rapamycin Response in Tumorigenic and Non-Tumorigenic Hepatic Cell Lines
por: Jimenez, Rosa H., et al.
Publicado: (2009)

Shedding of N-acetylglucosaminyltransferase-V is regulated by maturity of cellular N-glycan
por: Hirata, Tetsuya, et al.
Publicado: (2022)

Matrix Metalloproteinase-9 Production by Immortalized Human Chondrocyte Lines
por: Malemud, Charles J., et al.
Publicado: (2016)

Knockdown of CCNO decreases the tumorigenicity of gastric cancer by inducing apoptosis
por: Li, Lan, et al.
Publicado: (2018)

Triptolide inhibits cell proliferation and tumorigenicity of human neuroblastoma cells
por: YAN, XIAOMIN, et al.
Publicado: (2015)

FOXP1 inhibits cell growth and attenuates tumorigenicity of neuroblastoma
por: Ackermann, Sandra, et al.
Publicado: (2014)

JMJD6 is a tumorigenic factor and therapeutic target in neuroblastoma
por: Wong, Matthew, et al.
Publicado: (2019)

Matrix metalloproteinases in human melanoma cell lines and xenografts: increased expression of activated matrix metalloproteinase-2 (MMP-2) correlates with melanoma progression
por: Hofmann, U B, et al.
Publicado: (1999)

Differential effects of human and plant N-acetylglucosaminyltransferase I (GnTI) in plants
por: Henquet, Maurice, et al.
Publicado: (2009)

The transmembrane domain of N –acetylglucosaminyltransferase I is the key determinant for its Golgi subcompartmentation
por: Schoberer, Jennifer, et al.
Publicado: (2014)

N-acetylglucosaminyltransferase II Is Involved in Plant Growth and Development Under Stress Conditions
por: Yoo, Jae Yong, et al.
Publicado: (2021)

Examination of differential glycoprotein preferences of N-acetylglucosaminyltransferase-IV isozymes a and b
por: Osada, Naoko, et al.
Publicado: (2022)

Knockdown of NAT12/NAA30 reduces tumorigenic features of glioblastoma-initiating cells
por: Mughal, Awais A., et al.
Publicado: (2015)

STAT3 Knockdown Reduces Pancreatic Cancer Cell Invasiveness and Matrix Metalloproteinase-7 Expression in Nude Mice
por: Li, Hai dong, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_75tmih2v9jnuma53k48bk2tfqc