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Melatonin decreases cocaine-induced locomotor activity in pinealectomized rats
OBJECTIVE: Several studies have shown that the time of day regulates the reinforcing effects of cocaine. Additionally, melatonin and its MT(1) and MT(2) receptors have been found to participate in modulation of the reinforcing effects of such addictive drugs as cocaine. Loss of the diurnal variation...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Associação Brasileira de Psiquiatria
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236171/ https://www.ncbi.nlm.nih.gov/pubmed/31859790 http://dx.doi.org/10.1590/1516-4446-2018-0400 |