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Polygenic risk scores: from research tools to clinical instruments

Genome-wide association studies have shown unequivocally that common complex disorders have a polygenic genetic architecture and have enabled researchers to identify genetic variants associated with diseases. These variants can be combined into a polygenic risk score that captures part of an individ...

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Detalles Bibliográficos
Autores principales:	Lewis, Cathryn M., Vassos, Evangelos
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236300/ https://www.ncbi.nlm.nih.gov/pubmed/32423490 http://dx.doi.org/10.1186/s13073-020-00742-5

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