Hydroxychloroquine and short-course radiotherapy in elderly patients with newly diagnosed high-grade glioma: a randomized phase II trial

BACKGROUND: Effective treatment for patients at least 70 years with newly diagnosed glioblastoma remains challenging and alternatives to conventional cytotoxics are appealing. Autophagy inhibition has shown promising efficacy and safety in small studies of glioblastoma and other cancers. METHODS: We...

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Detalles Bibliográficos
Autores principales: Brazil, Lucy, Swampillai, Angela L, Mak, Ka Man, Edwards, Darren, Mesiri, Pavlina, Clifton-Hadley, Laura, Shaffer, Richard, Lewis, Joanne, Watts, Colin, Jeffries, Sarah, Gkogkou, Pinelopi, Chalmers, Anthony J, Fersht, Naomi L, Hackshaw, Allan, Short, Susan C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Clinical Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236384/
https://www.ncbi.nlm.nih.gov/pubmed/32642699
http://dx.doi.org/10.1093/noajnl/vdaa046

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