Burden and correlates of atrial fibrillation among hypertensive patients attending a tertiary hospital in Tanzania

BACKGROUND: Atrial fibrillation (AF) is the most common supra ventricular cardiac arrhythmia, which presents with variety of clinical symptoms. Hypertension increases risk of developing Atrial fibrillation by 1.5 fold. Together Atrial fibrillation and hypertension doubles the risk of morbidity and mortality. We aimed to determine the prevalence of AF and describe associated factors among hypertensive patients attending tertiary hospital in Tanzania. METHODS: A cross-sectional hospital-based study, involving 391 hypertensive patients visiting the Jakaya Kikwete Cardiac Institute was conducted between October to December 2017. Categorical variables were analyzed using chi square while student t- test was used to analyze continuous variables. Multivariate logistic regression analysis was performed to determine factors associated with AF. All analysis was two sided and p- value of < 0.05 was used to be not significant. RESULTS: AF was detected in 40 (10.2%) patients. Atrial fibrillation was associated with BMI ≥ 25 (OR 4.4, 95% CI 1.1–7.7, p-value 0.02), ejection fraction < 50% (OR 3.0, 95%CI 1.1–8.2, p-value 0.03), Left Atrial diameter > 40 mm (OR 9.4,95%CI 2.1–43.2, p-value < 0.01) and eGFR< 60 (OR 2.9, 95%CI 1.1–7.8, p-value 0.04). CONCLUSION: Atrial fibrillation is considerably prevalent among the hypertensive sub-population. Prompt diagnosis and timely management is vital to prevent complications and premature mortality.