Crystallization-Induced Diastereoisomer Transformation of Dihydroartemisinic Aldehyde with the Betti Base

[Image: see text] Artemisinin is an important drug to fight malaria. It is produced either by extraction or via a semisynthetic route involving enzyme engineering. A key intermediate to produce artemisinin by the enzymatic route is dihydroartemisinic aldehyde (DHAAl). However, control of the absolut...

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Detalles Bibliográficos
Autores principales: Zanetti, Andrea, Chaumont-Olive, Pauline, Schwertz, Geoffrey, Nascimento de Oliveira, Marllon, Gomez Fernandez, Mario Andrés, Amara, Zacharias, Cossy, Janine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237042/
https://www.ncbi.nlm.nih.gov/pubmed/32454580
http://dx.doi.org/10.1021/acs.oprd.9b00481

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237042/
https://www.ncbi.nlm.nih.gov/pubmed/32454580
http://dx.doi.org/10.1021/acs.oprd.9b00481

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