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Single nucleotide polymorphisms affect RNA-protein interactions at a distance through modulation of RNA secondary structures
Single nucleotide polymorphisms are widely associated with disease, but the ways in which they cause altered phenotypes are often unclear, especially when they appear in non-coding regions. One way in which non-coding polymorphisms could cause disease is by affecting crucial RNA-protein interactions...
Autores principales: | Shatoff, Elan, Bundschuh, Ralf |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237046/ https://www.ncbi.nlm.nih.gov/pubmed/32379750 http://dx.doi.org/10.1371/journal.pcbi.1007852 |
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