Cargando…

Separable, Ctf4-mediated recruitment of DNA Polymerase α for initiation of DNA synthesis at replication origins and lagging-strand priming during replication elongation

During eukaryotic DNA replication, DNA polymerase alpha/primase (Pol α) initiates synthesis on both the leading and lagging strands. It is unknown whether leading- and lagging-strand priming are mechanistically identical, and whether Pol α associates processively or distributively with the replisome...

Descripción completa

Detalles Bibliográficos
Autores principales:	Porcella, Sarina Y., Koussa, Natasha C., Tang, Colin P., Kramer, Daphne N., Srivastava, Priyanka, Smith, Duncan J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237047/ https://www.ncbi.nlm.nih.gov/pubmed/32379761 http://dx.doi.org/10.1371/journal.pgen.1008755

Ejemplares similares

Post-replicative nick translation occurs on the lagging strand during prolonged depletion of DNA ligase I in Saccharomyces cerevisiae
por: Koussa, Natasha C, et al.
Publicado: (2021)

Replicative DNA polymerases promote active displacement of SSB proteins during lagging strand synthesis
por: Cerrón, Fernando, et al.
Publicado: (2019)

DNA Replication Through Strand Displacement During Lagging Strand DNA Synthesis in Saccharomyces cerevisiae
por: Giannattasio, Michele, et al.
Publicado: (2019)

Chromatin Controls DNA Replication Origin Selection, Lagging-Strand Synthesis, and Replication Fork Rates
por: Kurat, Christoph F., et al.
Publicado: (2017)

Mismatch Repair Balances Leading and Lagging Strand DNA Replication Fidelity
por: Lujan, Scott A., et al.
Publicado: (2012)

Mechanism of strand displacement synthesis by DNA replicative polymerases
por: Manosas, Maria, et al.
Publicado: (2012)

Roles of DNA polymerase I in leading and lagging-strand replication defined by a high-resolution mutation footprint of ColE1 plasmid replication
por: Allen, Jennifer M., et al.
Publicado: (2011)

Ctf18-RFC and DNA Pol ϵ form a stable leading strand polymerase/clamp loader complex required for normal and perturbed DNA replication
por: Stokes, Katy, et al.
Publicado: (2020)

Roles for DNA polymerase δ in initiating and terminating leading strand DNA replication
por: Zhou, Zhi-Xiong, et al.
Publicado: (2019)

Bacillus subtilis DNA polymerases, PolC and DnaE, are required for both leading and lagging strand synthesis in SPP1 origin-dependent DNA replication
por: Seco, Elena M., et al.
Publicado: (2017)

Using the lagging strand to study chromosome replication
por: McGuffee, S, et al.
Publicado: (2013)

SV40 T antigen interactions with ssDNA and replication protein A: a regulatory role of T antigen monomers in lagging strand DNA replication
por: Onwubiko, Nichodemus O, et al.
Publicado: (2020)

Replicative DNA polymerases
por: Albà, M Mar
Publicado: (2001)

Priming DNA Replication from Triple Helix Oligonucleotides: Possible Threestranded DNA in DNA Polymerases
por: Lestienne, Patrick P.
Publicado: (2011)

Functional interplay of DnaE polymerase, DnaG primase and DnaC helicase within a ternary complex, and primase to polymerase hand-off during lagging strand DNA replication in Bacillus subtilis
por: Rannou, Olivier, et al.
Publicado: (2013)

APOBEC-induced mutations in human cancers are strongly enriched on the lagging DNA strand during replication
por: Seplyarskiy, Vladimir B., et al.
Publicado: (2016)

Limiting DNA polymerase delta alters replication dynamics and leads to a dependence on checkpoint activation and recombination-mediated DNA repair
por: Koussa, Natasha C., et al.
Publicado: (2021)

Dynamics of human replication factors in the elongation phase of DNA replication
por: Masuda, Yuji, et al.
Publicado: (2007)

The Replicative DnaE Polymerase of Bacillus subtilis Recruits the Glycolytic Pyruvate Kinase (PykA) When Bound to Primed DNA Templates
por: Holland, Alexandria, et al.
Publicado: (2023)

Lagging strand replication shapes the mutational landscape of the genome
por: Reijns, Martin A. M., et al.
Publicado: (2015)

DNA polymerase η contributes to genome-wide lagging strand synthesis
por: Kreisel, Katrin, et al.
Publicado: (2019)

Evidence that DNA polymerase δ contributes to initiating leading strand DNA replication in Saccharomyces cerevisiae
por: Garbacz, Marta A., et al.
Publicado: (2018)

The asymmetric distribution of RNA polymerase II and nucleosomes on replicated daughter genomes is caused by differences in replication timing between the lagging and the leading strand
por: Ziane, Rahima, et al.
Publicado: (2022)

Ctf4 Links DNA Replication with Sister Chromatid Cohesion Establishment by Recruiting the Chl1 Helicase to the Replisome
por: Samora, Catarina P., et al.
Publicado: (2016)

Synergism between CMG helicase and leading strand DNA polymerase at replication fork
por: Xu, Zhichun, et al.
Publicado: (2023)

Exonuclease mutations in DNA polymerase epsilon reveal replication strand specific mutation patterns and human origins of replication
por: Shinbrot, Eve, et al.
Publicado: (2014)

DNA polymerase ζ in DNA replication and repair
por: Martin, Sara K, et al.
Publicado: (2019)

Cycling of the E. coli lagging strand polymerase is triggered exclusively by the availability of a new primer at the replication fork
por: Yuan, Quan, et al.
Publicado: (2014)

Highly organized DnaA–oriC complexes recruit the single-stranded DNA for replication initiation
por: Ozaki, Shogo, et al.
Publicado: (2012)

Lagging Strand Initiation Processes in DNA Replication of Eukaryotes—Strings of Highly Coordinated Reactions Governed by Multiprotein Complexes
por: Nasheuer, Heinz Peter, et al.
Publicado: (2023)

Mcm10 regulates DNA replication elongation by stimulating the CMG replicative helicase
por: Lõoke, Marko, et al.
Publicado: (2017)

Replicative DNA polymerase mutations in cancer()
por: Heitzer, Ellen, et al.
Publicado: (2014)

Intensive DNA Replication and Metabolism during the Lag Phase in Cyanobacteria
por: Watanabe, Satoru, et al.
Publicado: (2015)

Plant organellar DNA polymerases are replicative and translesion DNA synthesis polymerases
por: Baruch-Torres, Noe, et al.
Publicado: (2017)

Distinct Double- and Single-Stranded DNA Binding of E. coli Replicative DNA Polymerase III α Subunit
por: McCauley, Micah J., et al.
Publicado: (2008)

Impact of the DNA polymerase Theta on the DNA replication program
por: Baldacci, Giuseppe, et al.
Publicado: (2014)

DNA Polymerase Gamma in Mitochondrial DNA Replication and Repair
por: Copeland, William C., et al.
Publicado: (2003)

DNA Helicase–Polymerase Coupling in Bacteriophage DNA Replication
por: Lo, Chen-Yu, et al.
Publicado: (2021)

Error-prone bypass of DNA lesions during lagging strand replication is a common source of germline and cancer mutations
por: Seplyarskiy, Vladimir B., et al.
Publicado: (2018)

CAF-1 deposits newly synthesized histones during DNA replication using distinct mechanisms on the leading and lagging strands
por: Rouillon, Clément, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_nhuhg73keq3bcna833g53sqimg