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Good Visual Outcome Following Corticosteroid Treatment for Compressive Optic Neuropathy Secondary to Sinonasal Carcinoma

Most patients with sinonasal carcinoma present to the otorhinolaryngologist with nasal symptoms. It is however uncommon for them to present with acute visual loss at first presentation. We report a case of compressive optic neuropathy secondary to sinonasal carcinoma, which presented acutely with ri...

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Autores principales: Mohammad Razali, Amirah, Mohd Zain, Ayesha, Bt Wan Abdul Halim, Wan Haslina, Md Din, Norshamsiah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237059/
https://www.ncbi.nlm.nih.gov/pubmed/32440379
http://dx.doi.org/10.7759/cureus.7732
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author Mohammad Razali, Amirah
Mohd Zain, Ayesha
Bt Wan Abdul Halim, Wan Haslina
Md Din, Norshamsiah
author_facet Mohammad Razali, Amirah
Mohd Zain, Ayesha
Bt Wan Abdul Halim, Wan Haslina
Md Din, Norshamsiah
author_sort Mohammad Razali, Amirah
collection PubMed
description Most patients with sinonasal carcinoma present to the otorhinolaryngologist with nasal symptoms. It is however uncommon for them to present with acute visual loss at first presentation. We report a case of compressive optic neuropathy secondary to sinonasal carcinoma, which presented acutely with right eye blurring of vision upon waking up. Computed tomography (CT) of the brain and orbit with contrast showed a locally invasive nasopharyngeal mass extending into the right orbit and cranial fossa. Histopathological examination revealed squamous cell sinonasal carcinoma. Her visual acuity improved with a three-day course of pulsed intravenous methylprednisolone 1 g per day, followed by a gradual tapering dose of oral prednisolone (1 mg/kg/day).
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spelling pubmed-72370592020-05-21 Good Visual Outcome Following Corticosteroid Treatment for Compressive Optic Neuropathy Secondary to Sinonasal Carcinoma Mohammad Razali, Amirah Mohd Zain, Ayesha Bt Wan Abdul Halim, Wan Haslina Md Din, Norshamsiah Cureus Ophthalmology Most patients with sinonasal carcinoma present to the otorhinolaryngologist with nasal symptoms. It is however uncommon for them to present with acute visual loss at first presentation. We report a case of compressive optic neuropathy secondary to sinonasal carcinoma, which presented acutely with right eye blurring of vision upon waking up. Computed tomography (CT) of the brain and orbit with contrast showed a locally invasive nasopharyngeal mass extending into the right orbit and cranial fossa. Histopathological examination revealed squamous cell sinonasal carcinoma. Her visual acuity improved with a three-day course of pulsed intravenous methylprednisolone 1 g per day, followed by a gradual tapering dose of oral prednisolone (1 mg/kg/day). Cureus 2020-04-18 /pmc/articles/PMC7237059/ /pubmed/32440379 http://dx.doi.org/10.7759/cureus.7732 Text en Copyright © 2020, Mohammad Razali et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Ophthalmology
Mohammad Razali, Amirah
Mohd Zain, Ayesha
Bt Wan Abdul Halim, Wan Haslina
Md Din, Norshamsiah
Good Visual Outcome Following Corticosteroid Treatment for Compressive Optic Neuropathy Secondary to Sinonasal Carcinoma
title Good Visual Outcome Following Corticosteroid Treatment for Compressive Optic Neuropathy Secondary to Sinonasal Carcinoma
title_full Good Visual Outcome Following Corticosteroid Treatment for Compressive Optic Neuropathy Secondary to Sinonasal Carcinoma
title_fullStr Good Visual Outcome Following Corticosteroid Treatment for Compressive Optic Neuropathy Secondary to Sinonasal Carcinoma
title_full_unstemmed Good Visual Outcome Following Corticosteroid Treatment for Compressive Optic Neuropathy Secondary to Sinonasal Carcinoma
title_short Good Visual Outcome Following Corticosteroid Treatment for Compressive Optic Neuropathy Secondary to Sinonasal Carcinoma
title_sort good visual outcome following corticosteroid treatment for compressive optic neuropathy secondary to sinonasal carcinoma
topic Ophthalmology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237059/
https://www.ncbi.nlm.nih.gov/pubmed/32440379
http://dx.doi.org/10.7759/cureus.7732
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