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Validation of a 10-Point Scoring System for Treatment of Cesarean Scar Pregnancy

PURPOSE: To validate a 10-point scoring system for the prediction of successful treatment modality in patients with cesarean scar pregnancy (CSP). PATIENTS AND METHODS: Data were collected from women seen between April 1, 2018, and June 30, 2019, at the Second Affiliated Hospital of Army Medical Uni...

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Autores principales: Tan, Ting-Ting, Sun, Qiu-Lei, Luo, Li, Chen, Zhu, Xiong, Xi, Xiang, Jin-Hong, Yan, Ping, Gao, Chun-Yan, Chen, Zheng-Qiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237119/
https://www.ncbi.nlm.nih.gov/pubmed/32523347
http://dx.doi.org/10.2147/TCRM.S243999
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author Tan, Ting-Ting
Sun, Qiu-Lei
Luo, Li
Chen, Zhu
Xiong, Xi
Xiang, Jin-Hong
Yan, Ping
Gao, Chun-Yan
Chen, Zheng-Qiong
author_facet Tan, Ting-Ting
Sun, Qiu-Lei
Luo, Li
Chen, Zhu
Xiong, Xi
Xiang, Jin-Hong
Yan, Ping
Gao, Chun-Yan
Chen, Zheng-Qiong
author_sort Tan, Ting-Ting
collection PubMed
description PURPOSE: To validate a 10-point scoring system for the prediction of successful treatment modality in patients with cesarean scar pregnancy (CSP). PATIENTS AND METHODS: Data were collected from women seen between April 1, 2018, and June 30, 2019, at the Second Affiliated Hospital of Army Medical University of China who were diagnosed with CSP and underwent evacuation, followed by uterine artery embolization (UAE) and successive laparoscopic local resection as salvage treatment if necessary. A score was computed based on clinical and ultrasonographic parameters included in a previously developed scoring system. Treatment indicated by the scoring system was compared with actual treatment received. Receiver operating characteristic (ROC) curves were used to identify cut-off scores for salvage treatment. RESULTS: Of 183 women, 108 were successfully treated by evacuation, 57 required UAE, and 18 eventually underwent laparoscopic surgery. Among 97 women scoring 0–4, 89 (91.8%) were treated by evacuation only. Of 69 women scoring between 5 and 7, 44 (63.8%) needed UAE following evacuation. Of 17 women scoring 8–10, 10 women (58.8%) underwent laparoscopic surgery. A cut-off of 4.145 was obtained by ROC curve for prediction of any salvage treatment; this was comparable to the scale’s conventional cut-off of 4. The cut-off score for women requiring laparoscopic surgery was 6.580, which was lower than 8 obtained in the scale’s initial validation. CONCLUSION: The overall performance of the 10-point scoring system was moderate for predicting successful treatment modalities of women with CSP, but the scale showed good predictive ability in recognizing women needing only evacuation before recovery.
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spelling pubmed-72371192020-06-09 Validation of a 10-Point Scoring System for Treatment of Cesarean Scar Pregnancy Tan, Ting-Ting Sun, Qiu-Lei Luo, Li Chen, Zhu Xiong, Xi Xiang, Jin-Hong Yan, Ping Gao, Chun-Yan Chen, Zheng-Qiong Ther Clin Risk Manag Original Research PURPOSE: To validate a 10-point scoring system for the prediction of successful treatment modality in patients with cesarean scar pregnancy (CSP). PATIENTS AND METHODS: Data were collected from women seen between April 1, 2018, and June 30, 2019, at the Second Affiliated Hospital of Army Medical University of China who were diagnosed with CSP and underwent evacuation, followed by uterine artery embolization (UAE) and successive laparoscopic local resection as salvage treatment if necessary. A score was computed based on clinical and ultrasonographic parameters included in a previously developed scoring system. Treatment indicated by the scoring system was compared with actual treatment received. Receiver operating characteristic (ROC) curves were used to identify cut-off scores for salvage treatment. RESULTS: Of 183 women, 108 were successfully treated by evacuation, 57 required UAE, and 18 eventually underwent laparoscopic surgery. Among 97 women scoring 0–4, 89 (91.8%) were treated by evacuation only. Of 69 women scoring between 5 and 7, 44 (63.8%) needed UAE following evacuation. Of 17 women scoring 8–10, 10 women (58.8%) underwent laparoscopic surgery. A cut-off of 4.145 was obtained by ROC curve for prediction of any salvage treatment; this was comparable to the scale’s conventional cut-off of 4. The cut-off score for women requiring laparoscopic surgery was 6.580, which was lower than 8 obtained in the scale’s initial validation. CONCLUSION: The overall performance of the 10-point scoring system was moderate for predicting successful treatment modalities of women with CSP, but the scale showed good predictive ability in recognizing women needing only evacuation before recovery. Dove 2020-05-15 /pmc/articles/PMC7237119/ /pubmed/32523347 http://dx.doi.org/10.2147/TCRM.S243999 Text en © 2020 Tan et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Tan, Ting-Ting
Sun, Qiu-Lei
Luo, Li
Chen, Zhu
Xiong, Xi
Xiang, Jin-Hong
Yan, Ping
Gao, Chun-Yan
Chen, Zheng-Qiong
Validation of a 10-Point Scoring System for Treatment of Cesarean Scar Pregnancy
title Validation of a 10-Point Scoring System for Treatment of Cesarean Scar Pregnancy
title_full Validation of a 10-Point Scoring System for Treatment of Cesarean Scar Pregnancy
title_fullStr Validation of a 10-Point Scoring System for Treatment of Cesarean Scar Pregnancy
title_full_unstemmed Validation of a 10-Point Scoring System for Treatment of Cesarean Scar Pregnancy
title_short Validation of a 10-Point Scoring System for Treatment of Cesarean Scar Pregnancy
title_sort validation of a 10-point scoring system for treatment of cesarean scar pregnancy
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237119/
https://www.ncbi.nlm.nih.gov/pubmed/32523347
http://dx.doi.org/10.2147/TCRM.S243999
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