Cargando…
Size, shape, and flexibility influence nanoparticle transport across brain endothelium under flow
Nanoparticle‐based therapeutic formulations are being increasingly explored for the treatment of various ailments. Despite numerous advances, the success of nanoparticle‐based technologies in treating brain diseases has been limited. Translational hurdles of nanoparticle therapies are attributed pri...
Autores principales: | Nowak, Maksymilian, Brown, Tyler D., Graham, Adam, Helgeson, Matthew E., Mitragotri, Samir |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237148/ https://www.ncbi.nlm.nih.gov/pubmed/32440560 http://dx.doi.org/10.1002/btm2.10153 |
Ejemplares similares
-
A microfluidic model of human brain (μHuB) for assessment of blood brain barrier
por: Brown, Tyler D., et al.
Publicado: (2019) -
Macrophages Recognize Size and Shape of Their Targets
por: Doshi, Nishit, et al.
Publicado: (2010) -
Platelet-like Nanoparticles: Mimicking Shape, Flexibility, and Surface Biology of Platelets To Target Vascular Injuries
por: Anselmo, Aaron C., et al.
Publicado: (2014) -
The Role of Tricellular Junctions in the Transport of Macromolecules Across Endothelium
por: Ghim, Mean, et al.
Publicado: (2020) -
Temperature dependence of protein transport across lymphatic endothelium in vitro
Publicado: (1984)