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Preparation for upcoming attentional states in the hippocampus and medial prefrontal cortex

Goal-directed attention is usually studied by providing individuals with explicit instructions on what they should attend to. But in daily life, we often use past experiences to guide our attentional states. Given the importance of memory for predicting upcoming events, we hypothesized that memory-g...

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Detalles Bibliográficos
Autores principales: Günseli, Eren, Aly, Mariam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237206/
https://www.ncbi.nlm.nih.gov/pubmed/32255423
http://dx.doi.org/10.7554/eLife.53191
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author Günseli, Eren
Aly, Mariam
author_facet Günseli, Eren
Aly, Mariam
author_sort Günseli, Eren
collection PubMed
description Goal-directed attention is usually studied by providing individuals with explicit instructions on what they should attend to. But in daily life, we often use past experiences to guide our attentional states. Given the importance of memory for predicting upcoming events, we hypothesized that memory-guided attention is supported by neural preparation for anticipated attentional states. We examined preparatory coding in the human hippocampus and mPFC, two regions that are important for memory-guided behaviors, in two tasks: one where attention was guided by memory and another in which attention was explicitly instructed. Hippocampus and mPFC exhibited higher activity for memory-guided vs. explicitly instructed attention. Furthermore, representations in both regions contained information about upcoming attentional states. In the hippocampus, this preparation was stronger for memory-guided attention, and occurred alongside stronger coupling with visual cortex during attentional guidance. These results highlight the mechanisms by which memories are used to prepare for upcoming attentional goals.
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spelling pubmed-72372062020-05-20 Preparation for upcoming attentional states in the hippocampus and medial prefrontal cortex Günseli, Eren Aly, Mariam eLife Neuroscience Goal-directed attention is usually studied by providing individuals with explicit instructions on what they should attend to. But in daily life, we often use past experiences to guide our attentional states. Given the importance of memory for predicting upcoming events, we hypothesized that memory-guided attention is supported by neural preparation for anticipated attentional states. We examined preparatory coding in the human hippocampus and mPFC, two regions that are important for memory-guided behaviors, in two tasks: one where attention was guided by memory and another in which attention was explicitly instructed. Hippocampus and mPFC exhibited higher activity for memory-guided vs. explicitly instructed attention. Furthermore, representations in both regions contained information about upcoming attentional states. In the hippocampus, this preparation was stronger for memory-guided attention, and occurred alongside stronger coupling with visual cortex during attentional guidance. These results highlight the mechanisms by which memories are used to prepare for upcoming attentional goals. eLife Sciences Publications, Ltd 2020-04-07 /pmc/articles/PMC7237206/ /pubmed/32255423 http://dx.doi.org/10.7554/eLife.53191 Text en © 2020, Günseli and Aly http://creativecommons.org/licenses/by/4.0/ http://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited.
spellingShingle Neuroscience
Günseli, Eren
Aly, Mariam
Preparation for upcoming attentional states in the hippocampus and medial prefrontal cortex
title Preparation for upcoming attentional states in the hippocampus and medial prefrontal cortex
title_full Preparation for upcoming attentional states in the hippocampus and medial prefrontal cortex
title_fullStr Preparation for upcoming attentional states in the hippocampus and medial prefrontal cortex
title_full_unstemmed Preparation for upcoming attentional states in the hippocampus and medial prefrontal cortex
title_short Preparation for upcoming attentional states in the hippocampus and medial prefrontal cortex
title_sort preparation for upcoming attentional states in the hippocampus and medial prefrontal cortex
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237206/
https://www.ncbi.nlm.nih.gov/pubmed/32255423
http://dx.doi.org/10.7554/eLife.53191
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