Intracerebral Transplantation of BDNF-overexpressing Human Neural Stem Cells (HB1.F3.BDNF) Promotes Migration, Differentiation and Functional Recovery in a Rodent Model of Huntington's Disease

Huntington’s disease (HD) is a dominantly inherited neurodegenerative disorder caused by abnormally expanded CAG repeats in the huntingtin gene. The huntingtin gene mutation leads to the progressive degeneration of striatal GABAergic medium spiny neurons (MSN) and reduces the level of brain-derived...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Hyun Sook, Jeon, Iksoo, Noh, Jeong-Eun, Lee, Hyunseung, Hong, Kwan Soo, Lee, Nayeon, Pei, Zhong, Song, Jihwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Brain and Neural Sciences 2020
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237270/
https://www.ncbi.nlm.nih.gov/pubmed/32408403
http://dx.doi.org/10.5607/en20011

Ejemplares similares

Ejemplares similares