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Establishment of an in vitro RNA polymerase transcription system: a new tool to study transcriptional activation in Borrelia burgdorferi

The Lyme disease spirochete Borrelia burgdorferi exhibits dramatic changes in gene expression as it transits between its tick vector and vertebrate host. A major hurdle to understanding the mechanisms underlying gene regulation in B. burgdorferi has been the lack of a functional assay to test how ge...

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Detalles Bibliográficos
Autores principales: Boyle, William K., Hall, Laura S., Armstrong, Anthony A., Dulebohn, Daniel P., Samuels, D. Scott, Gherardini, Frank C., Bourret, Travis J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237435/
https://www.ncbi.nlm.nih.gov/pubmed/32427963
http://dx.doi.org/10.1038/s41598-020-65104-y

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