Multi-objective optimization of tumor response to drug release from vasculature-bound nanoparticles

The pharmacokinetics of nanoparticle-borne drugs targeting tumors depends critically on nanoparticle design. Empirical approaches to evaluate such designs in order to maximize treatment efficacy are time- and cost-intensive. We have recently proposed the use of computational modeling of nanoparticle...

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Detalles Bibliográficos
Autores principales: Chamseddine, Ibrahim M., Frieboes, Hermann B., Kokkolaras, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237449/
https://www.ncbi.nlm.nih.gov/pubmed/32427977
http://dx.doi.org/10.1038/s41598-020-65162-2

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