Somatic SF3B1 hotspot mutation in prolactinomas

The genetic basis and corresponding clinical relevance of prolactinomas remain poorly understood. Here, we perform whole genome sequencing (WGS) on 21 patients with prolactinomas to detect somatic mutations and then validate the mutations with digital polymerase chain reaction (PCR) analysis of tiss...

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Detalles Bibliográficos
Autores principales: Li, Chuzhong, Xie, Weiyan, Rosenblum, Jared S., Zhou, Jianyu, Guo, Jing, Miao, Yazhou, Shen, Yutao, Wang, Hongyun, Gong, Lei, Li, Mingxuan, Zhao, Sida, Cheng, Sen, Zhu, Haibo, Jiang, Tao, Ling, Shiying, Wang, Fei, Zhang, Hongwei, Zhang, Mingshan, Qu, Yanming, Zhang, Qi, Li, Guilin, Wang, Junmei, Ma, Jun, Zhuang, Zhengping, Zhang, Yazhuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237453/
https://www.ncbi.nlm.nih.gov/pubmed/32427851
http://dx.doi.org/10.1038/s41467-020-16052-8

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