Translational control of breast cancer plasticity

Plasticity of neoplasia, whereby cancer cells attain stem-cell-like properties, is required for disease progression and represents a major therapeutic challenge. We report that in breast cancer cells NANOG, SNAIL and NODAL transcripts manifest multiple isoforms characterized by different 5’ Untransl...

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Detalles Bibliográficos
Autores principales: Jewer, Michael, Lee, Laura, Leibovitch, Matthew, Zhang, Guihua, Liu, Jiahui, Findlay, Scott D., Vincent, Krista M., Tandoc, Kristofferson, Dieters-Castator, Dylan, Quail, Daniela F., Dutta, Indrani, Coatham, Mackenzie, Xu, Zhihua, Puri, Aakshi, Guan, Bo-Jhih, Hatzoglou, Maria, Brumwell, Andrea, Uniacke, James, Patsis, Christos, Koromilas, Antonis, Schueler, Julia, Siegers, Gabrielle M., Topisirovic, Ivan, Postovit, Lynne-Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237473/
https://www.ncbi.nlm.nih.gov/pubmed/32427827
http://dx.doi.org/10.1038/s41467-020-16352-z

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