CDH6 and HAGH protein levels in plasma associate with Alzheimer’s disease in APOE ε4 carriers

Many Alzheimer’s disease (AD) genes including Apolipoprotein E (APOE) are found to be expressed in blood-derived macrophages and thus may alter blood protein levels. We measured 91 neuro-proteins in plasma from 316 participants of the Rotterdam Study (incident AD = 161) using Proximity Extension Lig...

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Detalles Bibliográficos
Autores principales: Ahmad, Shahzad, Milan, Marta del Campo, Hansson, Oskar, Demirkan, Ayse, Agustin, Ruiz, Sáez, Maria E., Giagtzoglou, Nikolaos, Cabrera-Socorro, Alfredo, Bakker, Margot H. M., Ramirez, Alfredo, Hankemeier, Thomas, Stomrud, Erik, Mattsson-Carlgren, Niklas, Scheltens, Philip, van der Flier, Wiesje M., Ikram, M. Arfan, Malarstig, Anders, Teunissen, Charlotte E., Amin, Najaf, van Duijn, Cornelia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237496/
https://www.ncbi.nlm.nih.gov/pubmed/32427856
http://dx.doi.org/10.1038/s41598-020-65038-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237496/
https://www.ncbi.nlm.nih.gov/pubmed/32427856
http://dx.doi.org/10.1038/s41598-020-65038-5

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