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CDH6 and HAGH protein levels in plasma associate with Alzheimer’s disease in APOE ε4 carriers
Many Alzheimer’s disease (AD) genes including Apolipoprotein E (APOE) are found to be expressed in blood-derived macrophages and thus may alter blood protein levels. We measured 91 neuro-proteins in plasma from 316 participants of the Rotterdam Study (incident AD = 161) using Proximity Extension Lig...
Autores principales: | Ahmad, Shahzad, Milan, Marta del Campo, Hansson, Oskar, Demirkan, Ayse, Agustin, Ruiz, Sáez, Maria E., Giagtzoglou, Nikolaos, Cabrera-Socorro, Alfredo, Bakker, Margot H. M., Ramirez, Alfredo, Hankemeier, Thomas, Stomrud, Erik, Mattsson-Carlgren, Niklas, Scheltens, Philip, van der Flier, Wiesje M., Ikram, M. Arfan, Malarstig, Anders, Teunissen, Charlotte E., Amin, Najaf, van Duijn, Cornelia M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237496/ https://www.ncbi.nlm.nih.gov/pubmed/32427856 http://dx.doi.org/10.1038/s41598-020-65038-5 |
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