Battling COVID-19: using old weapons for a new enemy

Coronavirus disease-19 (COVID-19) has reached pandemic proportions. Most of the drugs that are being tried for the treatment have not been evaluated in any randomized controlled trials. The purpose of this review was to summarize the in-vitro and in-vivo efficacy of these drugs on Severe Acute Respi...

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Autores principales: Kumar, Rohit, Gupta, Nitin, Kodan, Parul, Mittal, Ankit, Soneja, Manish, Wig, Naveet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237624/
https://www.ncbi.nlm.nih.gov/pubmed/32454984
http://dx.doi.org/10.1186/s40794-020-00107-1
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author Kumar, Rohit
Gupta, Nitin
Kodan, Parul
Mittal, Ankit
Soneja, Manish
Wig, Naveet
author_facet Kumar, Rohit
Gupta, Nitin
Kodan, Parul
Mittal, Ankit
Soneja, Manish
Wig, Naveet
author_sort Kumar, Rohit
collection PubMed
description Coronavirus disease-19 (COVID-19) has reached pandemic proportions. Most of the drugs that are being tried for the treatment have not been evaluated in any randomized controlled trials. The purpose of this review was to summarize the in-vitro and in-vivo efficacy of these drugs on Severe Acute Respiratory Syndrome (SARS-CoV-2) and related viruses (SARS and Middle East Respiratory Syndrome) and evaluate their potential for re-purposing them in the management of COVID-19.
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spelling pubmed-72376242020-05-20 Battling COVID-19: using old weapons for a new enemy Kumar, Rohit Gupta, Nitin Kodan, Parul Mittal, Ankit Soneja, Manish Wig, Naveet Trop Dis Travel Med Vaccines Review Coronavirus disease-19 (COVID-19) has reached pandemic proportions. Most of the drugs that are being tried for the treatment have not been evaluated in any randomized controlled trials. The purpose of this review was to summarize the in-vitro and in-vivo efficacy of these drugs on Severe Acute Respiratory Syndrome (SARS-CoV-2) and related viruses (SARS and Middle East Respiratory Syndrome) and evaluate their potential for re-purposing them in the management of COVID-19. BioMed Central 2020-05-20 /pmc/articles/PMC7237624/ /pubmed/32454984 http://dx.doi.org/10.1186/s40794-020-00107-1 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Kumar, Rohit
Gupta, Nitin
Kodan, Parul
Mittal, Ankit
Soneja, Manish
Wig, Naveet
Battling COVID-19: using old weapons for a new enemy
title Battling COVID-19: using old weapons for a new enemy
title_full Battling COVID-19: using old weapons for a new enemy
title_fullStr Battling COVID-19: using old weapons for a new enemy
title_full_unstemmed Battling COVID-19: using old weapons for a new enemy
title_short Battling COVID-19: using old weapons for a new enemy
title_sort battling covid-19: using old weapons for a new enemy
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237624/
https://www.ncbi.nlm.nih.gov/pubmed/32454984
http://dx.doi.org/10.1186/s40794-020-00107-1
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