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Toward a Macaque Model of HIV-1 Infection: Roadblocks, Progress, and Future Strategies

The human-specific tropism of Human Immunodeficiency Virus Type 1 (HIV-1) has complicated the development of a macaque model of HIV-1 infection/AIDS that is suitable for preclinical evaluation of vaccines and novel treatment strategies. Several innate retroviral restriction factors, such as APOBEC3...

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Detalles Bibliográficos
Autores principales: Thippeshappa, Rajesh, Kimata, Jason T., Kaushal, Deepak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237640/
https://www.ncbi.nlm.nih.gov/pubmed/32477302
http://dx.doi.org/10.3389/fmicb.2020.00882