Seizures in an Immunocompetent Adult From Treatment of Latent Tuberculosis Infection: Is Isoniazid to Blame?

Isoniazid-induced seizures are a rare adverse reaction especially in immunocompetent adults. We report a case of a healthy man with seizures shortly after ingestion of his first therapeutic dose of isoniazid with rifapentine therapy for treatment of latent tuberculosis infection. Only 6 other simila...

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Autores principales: Navalkele, Bhagyashri, Bueno Rios, Maria X, Wofford, John D, Kumar, Vijay, Webb, Risa M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237819/
https://www.ncbi.nlm.nih.gov/pubmed/32462048
http://dx.doi.org/10.1093/ofid/ofaa144
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author Navalkele, Bhagyashri
Bueno Rios, Maria X
Wofford, John D
Kumar, Vijay
Webb, Risa M
author_facet Navalkele, Bhagyashri
Bueno Rios, Maria X
Wofford, John D
Kumar, Vijay
Webb, Risa M
author_sort Navalkele, Bhagyashri
collection PubMed
description Isoniazid-induced seizures are a rare adverse reaction especially in immunocompetent adults. We report a case of a healthy man with seizures shortly after ingestion of his first therapeutic dose of isoniazid with rifapentine therapy for treatment of latent tuberculosis infection. Only 6 other similar cases are reported in the literature.
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spelling pubmed-72378192020-05-26 Seizures in an Immunocompetent Adult From Treatment of Latent Tuberculosis Infection: Is Isoniazid to Blame? Navalkele, Bhagyashri Bueno Rios, Maria X Wofford, John D Kumar, Vijay Webb, Risa M Open Forum Infect Dis Brief Report Isoniazid-induced seizures are a rare adverse reaction especially in immunocompetent adults. We report a case of a healthy man with seizures shortly after ingestion of his first therapeutic dose of isoniazid with rifapentine therapy for treatment of latent tuberculosis infection. Only 6 other similar cases are reported in the literature. Oxford University Press 2020-04-23 /pmc/articles/PMC7237819/ /pubmed/32462048 http://dx.doi.org/10.1093/ofid/ofaa144 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Report
Navalkele, Bhagyashri
Bueno Rios, Maria X
Wofford, John D
Kumar, Vijay
Webb, Risa M
Seizures in an Immunocompetent Adult From Treatment of Latent Tuberculosis Infection: Is Isoniazid to Blame?
title Seizures in an Immunocompetent Adult From Treatment of Latent Tuberculosis Infection: Is Isoniazid to Blame?
title_full Seizures in an Immunocompetent Adult From Treatment of Latent Tuberculosis Infection: Is Isoniazid to Blame?
title_fullStr Seizures in an Immunocompetent Adult From Treatment of Latent Tuberculosis Infection: Is Isoniazid to Blame?
title_full_unstemmed Seizures in an Immunocompetent Adult From Treatment of Latent Tuberculosis Infection: Is Isoniazid to Blame?
title_short Seizures in an Immunocompetent Adult From Treatment of Latent Tuberculosis Infection: Is Isoniazid to Blame?
title_sort seizures in an immunocompetent adult from treatment of latent tuberculosis infection: is isoniazid to blame?
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237819/
https://www.ncbi.nlm.nih.gov/pubmed/32462048
http://dx.doi.org/10.1093/ofid/ofaa144
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